A SECRET WEAPON FOR MESENCHYMAL STEM CELLS THERAPY

IDO can be a fee-limiting enzyme for degrading tryptophan (Trp) to N-formylkynurenine. Apart from the mobile–cell Speak to prerequisite for MSC to induce T-cell tolerance, the lifestyle medium also inhibits the proliferation of activated T lymphocytes, a paracrine effect that partly is dependent upon the expression of IDO.188 The IDO-mediated con

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